เข้าสู่ระบบ

รองศาสตราจารย์ ดร.จรีภรณ์ เอกวัฒน์ชัย

Associate Professor Chareeporn Akekawatchai, Ph.D.

  • ความเชี่ยวชาญ:ภูมิคุ้มกันวิทยาระดับโมเลกุล / ภูมิคุ้มกันวิทยาโรคไวรัส / ชีววิทยาภูมิคุ้มกันโรคมะเร็ง
  • Research interests: Molecular Immunology / Viral immunology / Immunobiology of cancer
  • email: cakekawatchai@gmail.com
DEPARTMENT OF MEDICAL TECHNOLOGY
Research Articles
1.Tarnathummanan C, Soimanee T, Khattiya J, Sretapunya W, Phaonakrop N, Roytrakul S and Akekawatchai C*. Plasma proteomic profiles of patients with HIV infection and coinfection with hepatitis B/C virus undergoing anti-retroviral therapy (Accepted in Biomedical Reports)
2.Srisopa S, Pipatsatitpong D and Akekawatchai C*. Association of serum lipid profile with liver fibrosis in HCV-coinfected HIV patients on suppressive anti-retroviral therapy. Biomedical Reports 21: 146, 2024.
3.Phannasil P, Akekawatchai C, Jitrapakdee S. MicroRNA expression profiles associated with the metastatic ability of MDA MB 231 breast cancer cells. Oncol Lett. 2023 Jun 22;26(2):339. doi: 10.3892/ol.2023.13926. PMID: 37427352; PMCID: PMC10326657.
4.Yuenyongchaiwat K, Akekawatchai C. Effects of a pedometer-based walking home program plus resistance training on inflammatory cytokines and depression in Thai older people with sarcopenia: a three-arm randomized controlled trial. Clin Gerontol. 2022 Dec3;1-12 doi: 10.1080/07317115.2022.2150396. Online ahead of print.
5.Yuenyongchaiwat K, Akekawatchai C. Beneficial effects of walking-based home program for improving cardiorespiratory performance and physical activity in sarcopenic older people: a randomized controlled trial. Eur J Phys Rehabil Med. 2022 Dec;58(6):838-844.
6.Yuenyongchaiwat K, Akekawatchai C. Systemic inflammation in sarcopenia alter functional capacity in Thai community-dwelling older people: A preliminary observational study. Curr Aging Sci. 2022 Aug 4;15(3):274-281.
7.Yuenyongchaiwat K, Akekawatchai C. Prevalence and incidence of sarcopenia and low physical activity among community-dwelling older Thai people: a preliminary prospective cohort study 2-year follow-up. PeerJ. 2022 Apr 22;10:e13320. Doi: 10.7717/peerj.13320.
8.Akekawatchai C*, Phuegsilp C, Changsri K, Soimanee T and Sretapunya W. Genotyping and allelic distribution of IFN- +874T/A and TGF-1 -509C/T single-nucleotide polymorphisms in human immunodeficiency virus-infected Thais. J Med Virol. 2022;94(6):2882-2886.
9.Chareeporn Akekawatchai*, Khaimuk Changsri, Apikhun Tunkor, Chada Phuegsilp, Thanawan Soimanee, Madtika Fungkrajai, Thitiilat Chiraunyanann, Warisara Sretapunya. Lack of association between IFN-, CXCL10 and TGF-1 gene polymorphisms and liver complication in HIV-infected Thais. Asian Pac J Cancer Prev 2022 Apr 1;23(4):1279-1284.
10.Siraprapa Siritutsoontorn, Witchuda Sukjai, Steven Polyak, Chareeporn Akekawatchai, Sarawut Jitrapakdee. Differential growth inhibition, cell cycle arrest and apoptosis of MCF-7 and MDA-MB-231 cells to holocarboxylase synthase suppression. Biochem Biophys Res Commun. 2022 Feb 19;593:108-115.
11.Khanti Rattanapornsompong, Janya Khattiya, Patchariya Phannasil, Narumon Phaonakrop, Sittiruk Roytrakul, Sarawut Jitrapakdee*, Chareeporn Akekawatchai*. Impaired G2/M cell cycle arrest induces apoptosis in pyruvate carboxylase knockdown MDA-MB-231 cells. Biochem Biophys Rep 2021 Jan 12; 25:100903.
12.Phatchariya Phannasil, Sittiruk Roytrakul, Narumon Phaonakrop, Piengchai Kupradinun, Sirintip Budda, Chaniphun Butryee, Chareeporn Akekawatchai*and Siriporn Tuntipopipat*. Protein expression profiles underlying the preventive and therapeutic potentials of Moringa oleifera Lam against azoxymethane and dextran sodium sulfate-induced mouse colon carcinogenesis. Oncol lett. 2020: 1792-1802
13.Thitiilat Chiraunyanan, Khaimook Changri, Warisara Sretapanya, Kornanong Yuenyongchaiwat and Chareeporn Akekawatchai*. CXCL12 G801A polymorphism is associated with significant liver fibrosis in HIV-infected Thais: a cross-sectional study. Asian Pac J Allergy Immunol. 2019 Sep;37(3):162-170. doi: 10.12932/AP-160917-0162.
14.Nalin Wongkattiya, Chareeporn Akekawatchai, Panchana Sanuansermsri, Ian Hamilton Fraser, Chayanin Pratoomsoot and Donruedee Sanguansermsri. Cheminal compositions and biological properties of essential oils from Zanthoxylum Rhetasa (Roxb.) DC and Zanthoxylum Limoella Alston. Afr J Tradit Complement Altern Med 2018 15 (2): 12-18.
15.Akekawatchai C*, Roytrakul S, Kittisenachai S, Isarankura-Na-Ayudhya S and Jitrapakdee S. Protein profiles associated with anoikis resistance of the metastatic MDA-MB-231 breast cancer cells. Asian Pac J Cancer Prev. 2016 March;17 (2):581-90.
16.Akekawatchai C*, Sretapanya W, Pipatsatitpong D and Chuenchit T. Hepatitis B and C virus coinfection and risks for the transaminitis in HIV-infected Thais on Combined anti-retroviral therapy. Asian Biomedicine 2015 June 9; 3: 353-361
17.Meizhi N, Klingler-Hoffmann M, Brazzatti J, Forbes B, Akekawatchai C, Hoffmann P, McColl SR. Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line. Proteome Sci. 2013 Jan 15; 11(1): 4: 5956-11-4.
18.Holland JD, Kochetkova M, Akekawatchai C, Dottore M, Lopez A and McColl SR. Differential functional activation of chemokine receptor CXCR4 is mediated by G-proteins in breast cancer cells. Cancer Res. 2006 Apr 15; 66(8):4117-24.
19.Akekawatchai C, Holland JD, Kochetkova M, Wallace JC and McColl SR. Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells. J Biol Chem. 2005 Dec 2; 280(48): 39701-8.
20.Ubol S, Sukwattanapan C, Maneerat Y. Inducible nitric oxide synthase inhibition delays death of rabies virus–infected mice. J Med Microbiol. 2001; 50: 238-242.
21.Ubol S, Sukwattanapan C, Utaisincharoen P. Rabies virus replication induced Bax-related, caspase-dependent apoptosis in mouse neuroblastoma cell. Virus Research. 1998; 56: 207-215.
22. Somkid Srisopa, Duangnate Pipatsatitpong and Chareeporn Akekawatchai* Genotypic distribution of hepatitis C virus in human immunodeficiency virus-infected patients in Bamrasnaradura Infectious Diseases Institute J Med Tech Assoc Thailand. 2020 April; 48 (1): 7215-7226.
23. Police P, Duangchanda T, Akekawatchai C, Fukpho W, Changsri P. Development of in-house SYBR green I qPCR with melting curve analysis for detection of basal core promoter A1762T/G1764A mutation of Hepatitis B virus. J Med Tech Assoc Thailand. 2019 December; 47 (3): 7159-7172.
24. Apikhun Tunkor, Khaimook Changri, Thitiilat Chiraunyanan, Warisara Sretapanya and Chareeporn Akekawatchai*. Association of CXCL10 G-201A/C-1596T polymorphisms with Hepatitis B and C infection in human immunodeficiency virus-infected Thais. J Med Tech Assoc Thailand 2018 Dec; 46 (3):6692-6706.
25. Warisara Sretapanya, Thitiilat Chiraunyanan, Duangnate Pipatsatitpong, Thippawan Chuenchitra and Chareeporn Akekawatchai*. Prevalence of heptotoxicity and factors associated with transaminitis in HIV-infected Thais without hepatitis B and C coinfection. J Med Tech Assoc Thailand 2017 Dec; 45(3):6140-6156.
Research Grants
1. 2020-present Research Unit in Diagnostic Molecular Biology of Chronic Diseases related to Cancer (DMB-CDC), supported by Thammasat University (Head of research unit)
2. 2022-2023 Development of biomarkers for chronic liver complication in human immunodeficiency virus-infected Thais, Thailand Science Research and Innovation Fundamental Fund through Thammasat University (Principal investigator)
3. 2024 Inflammaging in human immunodeficiency virus-infected Thais, supported by Thailand Science Research and Innovation Fundamental Fund fiscal year 2024 (Principal Investigator)
Awards
1. Chareeporn Akekawatchai, Apikul Tunkor, Chada Feugsil, Thitiilat Chiraunyanann, Warisara Sretapanya, Thanawan Soymanee, Khaimook Changsri and Kornanong Yuenyongchaiwat. Relationships between cytokine and chemokine gene polymorphisms and liver fibrosis in HIV-infected Thais. The 48th Annual Scientific Meeting of The Australian and New Zealand Society for Immunology. Adelaide Convention Centre, Adelaide, Australia, December 8-12, 2019 (Poster presentation)
2. Thitimonrat Doungchanda, Khaimuk Changsri, Thanawan Soimanee, Woraporn Fukpho, Duangnate Pipatsatitpong and Chareeporn Akekawatchai. Distribution and clinical significance of hepatitis B virus A1762T/G1764A double mutation in chronic hepatitis B patients: A cross-sectional study. 8th FIMSA Congress Immunology for Humanity. BEXCO, Busan, Korea, October 31-November 3, 2021 (Poster presentation)
3. Chareeporn Akekawatchai. Plasma Proteomic Analysis in People Living with HIV Predicts Progression to Advanced Liver Disease. International Conference of TU Health Science, The Future of Health Science: Integrating AI, Big Data, and Inclusive Education for Universal Well-Being, Thammasat University, 30-31 May 2024, Thammasat Medical Skill and Education Center (TMED), Thammasat University. (The Best Oral Presentation Award)
Textbooks/Books
1. Chareeporn Akekawatchai, Marina Kochetkova, Jane Holland and Shaun R. McColl. Chemokine receptor signal transduction in metastatic and nonmetastatic cancer cells. In: Chemokine Receptors and Cancer. A. Fulton (Ed) Human press, a part of Springer Science, 2009.
2. Akekawatchai C, Roytrakul S, Phaonakrop N, Jaresitthikunchai J, Jitrapakdee S. Proteomic analysis of the anoikis-resistant human breast cancer cell lines. Methods Mol Biol. 2020; 2138:185-193. doi: 10.1007/978-1-0716-0471-7_11.
3. Akekawatchai C, Sarawut Jitrapakdee. Cellular signals integrate cell cycle and metabolic control in cancer. Adv Protein Chem Struct Biol, 2023;135:397-423.
Patents/Petty Patents/Copyrights
No data was found
Faculty of Allied Health Sciences | Thammasat University